Department of Neurosurgery, Medical University, Copernicus Memorial Hospital, Łódź, Poland.
Folia Neuropathol. 2010;48(3):212-6.
Authors present a case of a 57-year-old woman with primary spinal cord malignant melanoma. Intramedullary localization of primary melanoma is extremely rare. The patient presented neurological deficits such as lower limbs paresis and sensory loss. MRI examination showed intramedullar tumor located on the Th10 vertebra level. Surgical treatment with total removal of tumor was performed. Histopathological study confirmed melanoma. Subsequent chemotherapy was given. Tumor was successfully treated by neurosurgery; radio- and chemotherapy with disease free follow up of 9 months. Surgical treatment of melanoma in this location is extremely important as it leads to regression of neurological symptoms and improvement of the quality of life.
作者报告了一例 57 岁女性原发性脊髓恶性黑色素瘤。原发性黑色素瘤的髓内定位极其罕见。患者表现为下肢瘫痪和感觉丧失等神经功能缺损。MRI 检查显示位于第 10 胸椎水平的髓内肿瘤。行肿瘤全切除的手术治疗。组织病理学研究证实为黑色素瘤。随后给予化疗。神经外科手术成功治疗肿瘤,无疾病进展随访 9 个月。该部位黑色素瘤的手术治疗非常重要,因为它可以使神经症状消退,提高生活质量。