Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Kyiv D0368, Ukraine.
J Photochem Photobiol B. 2011 Jan 10;102(1):32-8. doi: 10.1016/j.jphotobiol.2010.09.002. Epub 2010 Sep 21.
UV-shielding property, photocatalytic activity and cytotoxicity (including photocytotoxicity) of citrate-stabilized ceria colloid solutions were studied. It was established that UV-shielding property (namely, the sun protection factor, the critical absorption wavelength and the UVA/UVB-ratio) of ceria nanoparticles are as good as those of titanium dioxide and zinc oxide nanoparticles. It was further demonstrated that ceria nanoparticles possesses substantially lower photocatalytic activity, which additionally decreases upon decrease in ceria particle size. It was found that colloid ceria solutions are non-toxic to mouse fibroblasts (L929) and fibroblast-like cells of African Green monkey (VERO). Moreover, ceria nanoparticles are capable to protect these cells from UV-irradiation-induced damage. It was proposed that nanocrystalline ceria could be used not only as UV-blocking material, but also as prophylactic and even therapeutic compound for sunburns treatment.
研究了柠檬酸稳定的铈胶体溶液的遮光性能、光催化活性和细胞毒性（包括光细胞毒性）。结果表明，铈纳米粒子的遮光性能（即防晒系数、临界吸收波长和 UVA/UVB 比值）与二氧化钛和氧化锌纳米粒子相当。进一步证明，铈纳米粒子的光催化活性要低得多，而且随着铈颗粒尺寸的减小而进一步降低。研究发现胶体铈溶液对小鼠成纤维细胞（L929）和非洲绿猴成纤维样细胞（VERO）无毒。此外，铈纳米粒子能够保护这些细胞免受紫外线照射引起的损伤。研究提出，纳米晶氧化铈不仅可以用作紫外线阻断材料，还可以用作预防甚至治疗晒伤的化合物。
