Department of Pharmacognosy, Faculty of Pharmacy, Zabol University of Medical Sciences, Zabol, Iran.
Department of Chemical Engineering, Sahand University of Technology, Tabriz, Iran.
Bioprocess Biosyst Eng. 2021 Sep;44(9):1891-1899. doi: 10.1007/s00449-021-02569-9. Epub 2021 Apr 23.
Nanomaterials, as an active ingredient, have been widely deployed in various science and technological applications with zinc and titanium oxides nanoparticles being commonly applied in sunscreens. On similar lines, cerium oxide nanoparticles (CeO-NPs) were synthesized using Musa sapientum peel extract, to investigate its cytotoxic effects, UV protection and photocatalytic activity. The synthesized nanoparticles were identified through Raman, Powder X-ray Diffraction (PXRD), Fourier-Transform Infrared spectroscopy (FT-IR), Transmission Electron Microscopy (TEM), Field Emission Scanning Electron Microscopy (FESEM) and Energy-Dispersive Spectroscopy (EDX). FESEM results showed that the size of synthesized nanoparticles is in the range 4-13 nm. Their cytotoxic activity revealed a non-toxic behavior in concentrations below 500 μg/mL on lung (A549) cell lines. The Sun protection factor (SPF) was estimated approximately ~ 40 for synthesized CeO-NPs. The survey of photocatalytic activity showed that synthesized nanoparticles can remove 81.7% of AO7 in 180 min under visible light.
纳米材料作为一种活性成分，已广泛应用于各种科学和技术应用中，氧化锌和二氧化钛纳米颗粒常用于防晒霜。类似地，使用芭蕉皮提取物合成了氧化铈纳米颗粒（CeO-NPs），以研究其细胞毒性、紫外线防护和光催化活性。通过拉曼、粉末 X 射线衍射（PXRD）、傅里叶变换红外光谱（FT-IR）、透射电子显微镜（TEM）、场发射扫描电子显微镜（FESEM）和能谱（EDX）对合成的纳米颗粒进行了鉴定。FESEM 结果表明，合成纳米颗粒的尺寸在 4-13nm 范围内。在浓度低于 500μg/mL 时，它们对肺（A549）细胞系的细胞毒性表现出非毒性行为。合成 CeO-NPs 的防晒因子（SPF）约为 40。光催化活性研究表明，合成的纳米颗粒在可见光下 180 分钟内可去除 81.7%的 AO7。
