Banting and Best Department of Medical Research, The Donnelly Centre, University of Toronto, 160 College Street, Toronto, ON, M5S 3E1, Canada.
Bioinformatics. 2010 Nov 15;26(22):2927-8. doi: 10.1093/bioinformatics/btq562. Epub 2010 Oct 5.
The GeneMANIA Cytoscape plugin brings fast gene function prediction capabilities to the desktop. GeneMANIA identifies the most related genes to a query gene set using a guilt-by-association approach. The plugin uses over 800 networks from six organisms and each related gene is traceable to the source network used to make the prediction. Users may add their own interaction networks and expression profile data to complement or override the default data.
The GeneMANIA Cytoscape plugin is implemented in Java and is freely available at http://www.genemania.org/plugin/.
GeneMANIA Cytoscape 插件为桌面用户带来了快速的基因功能预测功能。GeneMANIA 使用关联性推断方法,根据查询基因集来确定最相关的基因。该插件使用来自六个生物体的 800 多个网络,并且每个相关基因都可以追溯到用于进行预测的源网络。用户可以添加自己的交互网络和表达谱数据,以补充或覆盖默认数据。
GeneMANIA Cytoscape 插件是用 Java 实现的,可以在 http://www.genemania.org/plugin/ 免费获得。