Biaduń W
Zakład Biologii i Parazytologii AM.
Wiad Parazytol. 1990;36(1-3):15-26.
The experiments were carried out on a group of 90 males of guinea pigs of 300 +/- 50 g in weight. The animals were divided into 6 groups equal in numbers. 5 of them were infected per os with ca 5000 invasive eggs of Ascaris suum. The blood of both infected and control guinea pigs was controlled on 1, 2, 4, 7, and 20th day after infection. The level of total lipids (according to Swahn method), WKT (Dole titrimetric method), total cholesterol and HDL cholesterol (Błaszczyszyn method) and triglycerides (colometric method) was determined. During the invasion, the decrease in all studied indicators was observed, and was particularly apparent on 4th and 7th day after infection. Only in case of WKT and tryglicerides a slight increase at initial stage of invasion was found. During larval ascariasis, as it appears, the metabolism of lipids is significantly disturbed. The changes are due to the break in liver function and, presumedly, changes in hormone secretion which are provoked by the presence of the parasite.
实验在一组体重为300±50克的90只雄性豚鼠身上进行。动物被分成数量相等的6组。其中5组经口感染约5000个猪蛔虫侵袭性虫卵。在感染后的第1、2、4、7和20天对感染组和对照组豚鼠的血液进行检测。测定总脂质水平（根据斯万法）、WKT（多尔滴定法）、总胆固醇和高密度脂蛋白胆固醇（布拉斯奇辛法）以及甘油三酯（比色法）。在感染期间，观察到所有研究指标均下降，在感染后第4天和第7天尤为明显。仅在WKT和甘油三酯方面，在感染初期发现有轻微升高。看来，在幼虫期蛔虫病期间，脂质代谢受到显著干扰。这些变化是由于肝功能受损以及推测由寄生虫存在引发的激素分泌变化所致。
