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强化 2 型糖尿病患者的多因素治疗:能取得什么成果,是否值得?

Intensified multifactorial treatment of patients with Type 2 diabetes: what can be achieved and does it pay off?

机构信息

University of Copenhagen and Steno-Hagedorn Diabetes Center, Copenhagen, Denmark.

出版信息

J Diabetes. 2009 Jun;1(2):83-9. doi: 10.1111/j.1753-0407.2009.00014.x.

DOI:10.1111/j.1753-0407.2009.00014.x
PMID:20929504
Abstract

By influencing the standards of diabetes care and treatment guidelines throughout the world, the results of recent long-term risk factor interventions in Type 2 diabetes (T2D) have likely contributed to the improved health outcomes and induced a decline in mortality in people with T2D. Although we have a need for even more evidence to support early, individualized, and intensive management of all known modifiable risk factors, we have now reached an era in T2D care where the critical challenges appear to be to translate the insights, knowledge and benefits to patients in the community setting. Current surveys show slow progress in achieving treatment goals and in the use of recommended drugs and adjustments of lifestyle for the prevention of vascular complications in diabetes. The resistance and barriers among medical professionals and patients likely have multiple causes. The present review focuses on experiences from multifactorial interventions in high-risk patients with T2D where it is possible to markedly improve their prognosis.

摘要

通过影响全球糖尿病护理和治疗指南的标准,最近对 2 型糖尿病(T2D)的长期危险因素干预的结果可能有助于改善 T2D 患者的健康结果并降低死亡率。尽管我们需要更多的证据来支持对所有已知可改变的危险因素进行早期、个体化和强化管理,但我们现在已经进入了 T2D 护理的一个新时代,其中关键的挑战似乎是将这些见解、知识和益处转化为社区环境中患者的利益。目前的调查显示,在实现治疗目标以及使用推荐药物和调整生活方式以预防糖尿病血管并发症方面进展缓慢。医疗专业人员和患者之间的阻力和障碍可能有多种原因。本综述重点介绍了在高危 T2D 患者中进行多因素干预的经验,在这些患者中,可以显著改善他们的预后。

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J Diabetes. 2009 Jun;1(2):83-9. doi: 10.1111/j.1753-0407.2009.00014.x.
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