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乳头瘤病毒及病毒特异性抗原在荷瘤南非多乳鼠(GRA吉森株)皮肤中的定位

Localization of papillomavirus and virus-specific antigens in the skin of tumor-bearing Mastomys natalensis (GRA Giessen).

作者信息

Reinacher M, Müller H, Thiel W, Rudolph R L

出版信息

Med Microbiol Immunol. 1978 Jul 4;165(2):93-9. doi: 10.1007/BF02122744.

DOI:10.1007/BF02122744
PMID:209298
Abstract

In skin neoplasms (so-called keratoakanthomas, papillomas, and squamous cell carcinomas) of Mastomys natalensis (GRA Giessen) virus particles and viral antigens were demonstrated in distinct epithelial layers. Nuclei of the upper parts of the stratum granulosum and disintegrated cell parts of the stratum corneum contain viral structures. The localization of virus particles and viral antigens in any skin neoplasms of M. natalensis (GRA Giessen) corresponded to the sites where papillomavirus-specific material had been demonstrated in papillomas of other species.

摘要

在南非多乳鼠(GRA吉森株)的皮肤肿瘤(所谓的角化棘皮瘤、乳头状瘤和鳞状细胞癌)中,病毒颗粒和病毒抗原在不同的上皮层中被证实。颗粒层上部的细胞核和角质层解体的细胞部分含有病毒结构。南非多乳鼠(GRA吉森株)任何皮肤肿瘤中病毒颗粒和病毒抗原的定位与在其他物种乳头状瘤中已证实的乳头瘤病毒特异性物质的部位相对应。

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