Lalya F, Ocheke I E, Hounnou-d'Almeida M, Sagbo G, Alao J, Antwi S, Ayivi B, Koumakpai S
Service de Pediatrie et de Genetique Medicale, Centre National Hospitalier et Universitaire Hubert K. Maga de Cotonou, Benin.
West Afr J Med. 2010 Jul-Aug;29(4):263-6.
BACKGROIUND: Tuberculosis (TB) is a public health problem. Knowing its patterns could help address it more efficiently.
To determine the hospital incidence, presentation, management, and outcome of TB in our setting.
We conducted a chart review of children with TB during a five-year period at the University Hospital CNHU-HKM, Cotonou, Benin.
Hospital prevalence of TB among hospitalised children was 0.2%. The mean age was six years, with a male:female ratio of 1.4:1. The common clinical features were: cough (78.1%), long standing fever (81.2%), growth retardation (65.6%), pulmonary consolidation (53.1%) and hepatosplenomegaly (34.4%). The skin tuberculin test was positive in only 40.6% of cases. Co-infection with HIV was present in 51.8% of cases. Mycobacterium tuberculosis could be identified in only 21.8% of cases. Twenty-six (81.2%) pulmonary tuberculosis (PTB) cases were diagnosed, eight (25%) of which were associated with extra pulmonary TB. Six (18.7%) presumed isolated extra PTB were also diagnosed. Eight-month treatment regimen was used in most patients, with mortality rate of 9.3%.
Although TB hospital prevalence seems low in our setting, management needs to be improved according to guidelines.
背景:结核病是一个公共卫生问题。了解其发病模式有助于更有效地应对该问题。
确定我院结核病的医院发病率、临床表现、治疗及转归情况。
我们对贝宁科托努CNHU-HKM大学医院五年期间的结核病患儿病历进行了回顾性研究。
住院儿童结核病的医院患病率为0.2%。平均年龄为6岁,男女比例为1.4:1。常见临床特征为:咳嗽(78.1%)、长期发热(81.2%)、生长发育迟缓(65.6%)、肺部实变(53.1%)和肝脾肿大(34.4%)。仅40.6%的病例结核菌素皮肤试验呈阳性。51.8%的病例合并感染HIV。仅21.8%的病例可鉴定出结核分枝杆菌。确诊26例(81.2%)肺结核(PTB)病例,其中8例(25%)合并肺外结核。还确诊了6例(18.7%)疑似孤立性肺外PTB。大多数患者采用8个月治疗方案,死亡率为9.3%。
尽管我院结核病的医院患病率似乎较低,但仍需根据指南改进管理。