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公共政策如何影响宫颈癌筛查和疫苗接种策略?

How does public policy impact cervical screening and vaccination strategies?

机构信息

Department of Obstetrics & Gynecology, Columbia University College of Physicians & Surgeons, New York, NY 10032, USA.

出版信息

Gynecol Oncol. 2010 Nov;119(2):175-80. doi: 10.1016/j.ygyno.2010.08.021.

Abstract

OBJECTIVES

To examine the current approaches to cervical screening and points to consider for improving HPV vaccination acceptance and uptake in the US.

METHODS

An expert forum was conducted September 12-13, 2008, by the Society of Gynecologic Oncologists including 56 experts in cervical cancer and titled "Future Strategies of Cervical Cancer Prevention: What Do We Need to Do Now to Prepare?".

RESULTS

Cervical cancer prevention has primarily relied on screening paradigms but vaccination against human papillomavirus (HPV), the cause of the disease, is a primary preventative measure that has been recommended by all cervical cancer screening stakeholders. Guidelines for vaccination are developed by national advisory groups, but successful implementation requires a supportive infrastructure and the cooperation of providers, clinicians, and patients. HPV vaccination has been available in the United States (US) since 2006 and screening practices have been updated to also include HPV genotyping. However, many clinicians fail to adhere to the guidelines for HPV testing (and HPV co-testing) as part of cervical cancer screening, and vaccination coverage has been poor among females aged 11 and 12, the group for which vaccination is recommended by all organizations.

CONCLUSIONS

The data reviewed and presented in this session of the "Future Strategies of Cervical Cancer Prevention. What Do We Need to do Now to Prepare?". The Forum suggests that the policies influencing HPV vaccination and screening need to be reassessed at multiple levels in order to achieve more effective implementation and regular use.

摘要

目的

研究美国目前的宫颈筛查方法,并探讨提高 HPV 疫苗接种率的注意事项。

方法

2008 年 9 月 12 日至 13 日,妇科肿瘤学家协会举办了一次专家论坛,该论坛由 56 名宫颈癌专家参与,题为“宫颈癌预防的未来策略:我们现在需要做些什么来准备?”。

结果

宫颈癌预防主要依赖于筛查模式,但针对导致该病的人乳头瘤病毒(HPV)的疫苗接种是一种主要的预防措施,已被所有宫颈癌筛查利益相关者推荐。疫苗接种指南由国家咨询小组制定,但成功实施需要支持性基础设施以及提供者、临床医生和患者的合作。HPV 疫苗自 2006 年以来已在美国上市,筛查实践已更新为包括 HPV 基因分型。然而,许多临床医生未能遵守 HPV 检测(和 HPV 联合检测)作为宫颈癌筛查一部分的指南,并且所有组织都建议接种疫苗的 11 岁和 12 岁女性的疫苗接种率一直很低。

结论

本次“宫颈癌预防的未来策略。我们现在需要做些什么来准备?”会议上回顾和介绍的数据。论坛表明,需要在多个层面重新评估影响 HPV 疫苗接种和筛查的政策,以实现更有效的实施和定期使用。

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