Huang Alison J, Pérez-Stable Eliseo J, Kim Sue E, Wong Sabrina T, Kaplan Celia P, Walsh Judith M E, Iwaoka-Scott A Yuri, Sawaya George F
Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.
J Gen Intern Med. 2008 Sep;23(9):1324-9. doi: 10.1007/s11606-008-0633-x. Epub 2008 May 28.
Human papillomavirus (HPV) testing is increasingly being used to determine the optimal cervical cancer screening interval in older women. Little is known about women's attitudes toward HPV testing or how these attitudes may influence medical discussions about cervical cancer screening.
Preferences for HPV and concomitant Papanicolaou (Pap) testing were assessed through in-person interviews with diverse women aged 50 to 80 years recruited from community and university-based practices.
Eight hundred and sixty-five women (257 White, 87 African American, 149 Latina, and 372 Asian) were interviewed. Approximately 60% of participants wanted to be tested for HPV and another 15% would undergo testing if recommended by their physician. Among those wanting HPV testing, 94% would want more frequent than annual Pap tests if they had a positive HPV test and a normal Pap test. Two thirds of those under age 65 would be willing to switch to triennial Pap testing, and half of those aged 65 and older would be willing to discontinue Pap testing, if they had a negative HPV test and normal Pap test. Preferences for testing varied by ethnicity, age, place of birth, and cancer history.
The majority of older women were willing to use HPV testing to make decisions about frequency and duration of cervical cancer screening, but up to one third would want at least annual, ongoing screening regardless of HPV test results. Efforts should be made to ensure that HPV testing is used to reinforce appropriate utilization of screening tests.
人乳头瘤病毒（HPV）检测越来越多地用于确定老年女性宫颈癌筛查的最佳间隔时间。对于女性对HPV检测的态度，以及这些态度如何影响关于宫颈癌筛查的医学讨论，我们知之甚少。
通过对从社区和大学医疗机构招募的50至80岁不同女性进行面对面访谈，评估她们对HPV检测和同时进行巴氏（Pap）检测的偏好。
共访谈了865名女性（257名白人、87名非裔美国人、149名拉丁裔和372名亚裔）。约60%的参与者希望进行HPV检测，另有15%的人表示如果医生建议就会接受检测。在希望进行HPV检测的人中，如果HPV检测呈阳性且巴氏检测正常，94%的人希望比每年进行一次巴氏检测的频率更高。如果HPV检测呈阴性且巴氏检测正常，65岁以下的人中三分之二愿意改为每三年进行一次巴氏检测，65岁及以上的人中一半愿意停止巴氏检测。检测偏好因种族、年龄、出生地和癌症病史而异。
大多数老年女性愿意使用HPV检测来决定宫颈癌筛查的频率和持续时间，但高达三分之一的人无论HPV检测结果如何，都希望至少每年进行一次持续筛查。应努力确保HPV检测用于加强筛查检测的合理利用。
