Department of Pharmacology, Centre for Toxicology, School of Pharmacy, University of London, London, UK.
J Neurosci Methods. 2010 Dec 15;194(1):102-7. doi: 10.1016/j.jneumeth.2010.09.018. Epub 2010 Oct 7.
The Basso, Beattie and Bresnahan (BBB) Locomotor Rating Scale is a standardized assessment scale for use in experimental spinal cord injury (SCI) research. This paper describes a computer program, ScoreCentre, which aims to simplify the recording and handling of BBB locomotor scale data. The program assists with the recording of observational data from open-field testing and then automatically calculates BBB scores. Possible errors associated with data entry and manual calculation of scores are thus essentially eliminated. In addition, significant time is saved by the automated derivation of scores and subscores and elimination of the need to manually transfer data from paper records to a computer. ScoreCentre can also be used as a training aid, to help familiarize users with the BBB scale and to explore how changes in the observations impact on overall BBB score. ScoreCentre includes simple experiment management functions such as control of trial blinding, administration of drugs in a blinded fashion and longitudinal data analysis. ScoreCentre provides all the advantages of electronic records, such as ease of use, analysis and archiving, and allows the elimination of paper records if appropriate. When paper records are required, for example for archiving and auditing, they can be automatically produced by ScoreCentre. ScoreCentre will assist with both the learning and use of the BBB locomotor scale, thus facilitating the use of this standardized outcome measure in SCI research. ScoreCentre is available to download from www.rmeonline.net/scorecentre.
巴索、比蒂和布雷沙恩（BBB）运动评分量表是一种用于实验性脊髓损伤（SCI）研究的标准化评估量表。本文介绍了一个名为 ScoreCentre 的计算机程序，旨在简化 BBB 运动评分量表数据的记录和处理。该程序有助于记录开阔场地测试中的观察数据，然后自动计算 BBB 评分。因此，基本上消除了与数据输入和手动计算评分相关的可能错误。此外，通过自动推导评分和子评分以及避免手动将数据从纸质记录转移到计算机，节省了大量时间。ScoreCentre 还可用作培训辅助工具，帮助用户熟悉 BBB 量表，并探索观察结果的变化如何影响整体 BBB 评分。ScoreCentre 包括简单的实验管理功能，如试验盲法控制、盲法给药和纵向数据分析。ScoreCentre 提供了电子记录的所有优势，如易用性、分析和归档，并允许在适当的情况下消除纸质记录。例如，当需要纸质记录进行归档和审核时，可以由 ScoreCentre 自动生成。ScoreCentre 将有助于学习和使用 BBB 运动评分量表，从而促进 SCI 研究中对这种标准化结果测量的使用。ScoreCentre 可从 www.rmeonline.net/scorecentre 下载。
