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为什么要对动物进行试验来治疗人类?论动物模型的有效性。

Why test animals to treat humans? On the validity of animal models.

作者信息

Shelley Cameron

机构信息

Centre for Society, Technology, and Values, University of Waterloo, Waterloo, ON N2L 3G1, Canada.

出版信息

Stud Hist Philos Biol Biomed Sci. 2010 Sep;41(3):292-9. doi: 10.1016/j.shpsc.2010.07.002. Epub 2010 Jul 31.

Abstract

Critics of animal modeling have advanced a variety of arguments against the validity of the practice. The point of one such form of argument is to establish that animal modeling is pointless and therefore immoral. In this article, critical arguments of this form are divided into three types, the pseudoscience argument, the disanalogy argument, and the predictive validity argument. I contend that none of these criticisms currently succeed, nor are they likely to. However, the connection between validity and morality is important, suggesting that critical efforts would be instructive if they addressed it in a more nuanced way.

摘要

动物模型的批评者提出了各种反对该做法有效性的论点。其中一种论点的要点是要证明动物模型毫无意义,因此是不道德的。在本文中,这种形式的批判性论点分为三种类型:伪科学论点、非类比论点和预测有效性论点。我认为目前这些批评都没有成功,而且也不太可能成功。然而,有效性与道德之间的联系很重要,这表明如果批判性努力能以更细致入微的方式来探讨这一联系,将会具有启发性。

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