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退伍军人事务部的重性抑郁障碍电抽搐治疗。

Electroconvulsive therapy for major depression within the Veterans Health Administration.

机构信息

Department of Veterans Affairs, Health Services Research and Development Center of Excellence, Ann Arbor, MI, United States.

出版信息

J Affect Disord. 2011 Apr;130(1-2):21-5. doi: 10.1016/j.jad.2010.09.023. Epub 2010 Oct 8.

Abstract

OBJECTIVES

Electroconvulsive therapy (ECT) is the most effective treatment for severe or treatment resistant depression; however, the lack of widely accepted methods for determining when ECT is indicated may contribute to disparities and variation in use. We examined receipt of ECT among depressed patients in the largest coordinated health system in the US, the Veterans Health Administration.

METHODS

Using administrative data, we conducted a multivariable logistic regression to identify individual clinical and sociodemographic predictors of receiving ECT, including variables of geographic accessibility to ECT, among patients diagnosed with major depressive disorder between 1999 and 2004.

RESULTS

307 (0.16%) of 187,811 patients diagnosed with major depression received ECT during the study period. Black patients were less likely to receive ECT than whites (odds ratio 0.33; 95% confidence interval: 0.20, 0.55), and patients living in the South (OR: 0.71; 95% CI: 0.53, 0.95) or West (OR: 0.59; 95% CI: 0.42, 0.82) were less likely to receive ECT than patients living in the central US. Patients whose closest VA facility provided ECT had a higher likelihood of receiving ECT (OR: 3.02; 95% CI: 2.22, 4.10). Depressed patients with no major medical comorbidities were also more likely to receive ECT (OR: 2.42; 95% CI: 1.65, 3.55).

LIMITATIONS

Findings are not adjusted for depression severity.

CONCLUSIONS

ECT use for major depression was relatively uncommon. Race, US region, geographic accessibility, and general medical health were all associated with whether or not patients received ECT. Clinicians and health systems should work to provide equitable access and more consistent use of this safe and effective treatment.

摘要

目的

电抽搐疗法(ECT)是治疗严重或治疗抵抗性抑郁症最有效的方法;然而,缺乏广泛接受的方法来确定何时需要 ECT 可能导致使用的差异和变化。我们在美国最大的协调医疗系统——退伍军人健康管理局,研究了患有抑郁症的患者接受 ECT 的情况。

方法

使用行政数据,我们进行了多变量逻辑回归分析,以确定个体临床和社会人口统计学预测因素与接受 ECT 的相关性,包括 ECT 地理可及性等变量,这些因素在 1999 年至 2004 年间被诊断患有重度抑郁症的患者中。

结果

在研究期间,187811 名被诊断患有重度抑郁症的患者中有 307 名(0.16%)接受了 ECT。黑人患者接受 ECT 的可能性低于白人(比值比 0.33;95%置信区间:0.20,0.55),居住在美国南部(OR:0.71;95%可信区间:0.53,0.95)或西部(OR:0.59;95%可信区间:0.42,0.82)的患者接受 ECT 的可能性低于居住在美国中部的患者。离患者最近的 VA 设施提供 ECT 的患者接受 ECT 的可能性更高(OR:3.02;95%置信区间:2.22,4.10)。没有主要合并症的抑郁症患者也更有可能接受 ECT(OR:2.42;95%置信区间:1.65,3.55)。

局限性

研究结果未经调整抑郁严重程度。

结论

ECT 治疗重度抑郁症的应用相对较少。种族、美国地区、地理可及性和一般医疗健康状况均与患者是否接受 ECT 相关。临床医生和医疗系统应努力提供公平的机会,并更一致地使用这种安全有效的治疗方法。

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