Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH 43210, USA.
Infect Dis Clin North Am. 2010 Dec;24(4):871-84, vii. doi: 10.1016/j.idc.2010.07.006.
Cholangiocarcinomas are rare malignant tumors whose incidence is increasing worldwide. Risk factors for this malignancy include both infectious and non-infectious diseases characterized by chronic inflammation of the bile duct epithelia. Diagnosis of these cancers remains difficult because of the lack of sensitive diagnostic tests. The prognosis is poor probably because of the lack of effective treatments for unresectable cancer.
胆管癌是一种罕见的恶性肿瘤，其发病率在全球范围内呈上升趋势。这种恶性肿瘤的危险因素包括以胆管上皮慢性炎症为特征的感染性和非传染性疾病。由于缺乏敏感的诊断检测方法，这些癌症的诊断仍然很困难。由于缺乏对不可切除癌症的有效治疗方法，预后较差。
