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提供经导管主动脉瓣植入服务对传统主动脉瓣手术活动的影响:前 2 年的患者风险因素和结局。

What is the impact of providing a transcatheter aortic valve implantation service on conventional aortic valve surgical activity: patient risk factors and outcomes in the first 2 years.

机构信息

University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK.

出版信息

Heart. 2010 Oct;96(20):1633-7. doi: 10.1136/hrt.2010.203661.

DOI:10.1136/hrt.2010.203661
PMID:20937751
Abstract

OBJECTIVES

To assess the impact of introducing a transcatheter aortic valve implantation (TAVI) service on aortic valve surgical activity and outcomes.

DESIGN

A retrospective analysis of prospectively collected data.

SETTING

University hospital of south Manchester.

PATIENTS

815 consecutive patients undergoing isolated aortic valve replacement (AVR) or coronary artery bypass grafting plus AVR from January 2006 to December 2009. Fifty consecutive patients who underwent TAVI from January 2008 to December 2009.

MAIN OUTCOME MEASURES

Aortic valve surgical activity in the 2years before the introduction of a TAVI service and in the 2years following. Outcomes following conventional aortic valve surgery and TAVI.

RESULTS

In the 2years following the introduction of TAVI at this centre, conventional AVR activity has increased by 37% compared with an 8% increase nationally (p<0.001). Compared with the 2years before TAVI there was no change in the mean logistic EuroSCORE (7.4 vs 7.9 p=0.16) or crude mortality rate (2.9% vs 2.1% p=0.48). Fifty high-risk patients underwent TAVI with a 30-day mortality rate of 0%. The mean logistic EuroSCORE of the TAVI patients was 25.3.

CONCLUSIONS

TAVI is an emerging alternative to AVR in high-risk patients. Since the introduction of a TAVI service at this centre, conventional AVR activity has increased. Despite a trend of increasing mean logistic EuroSCORE indicating that more complex cases are being undertaken, there has been a non-significant reduction in the crude mortality rate. Offering a TAVI service has a positive impact on the volume of conventional AVR surgical activity.

摘要

目的

评估经导管主动脉瓣植入术(TAVI)服务的引入对主动脉瓣手术活动和结果的影响。

设计

前瞻性收集数据的回顾性分析。

地点

南曼彻斯特大学医院。

患者

2006 年 1 月至 2009 年 12 月期间,连续 815 例接受单纯主动脉瓣置换术(AVR)或冠状动脉旁路移植术加 AVR 的患者。2008 年 1 月至 2009 年 12 月期间,连续 50 例接受 TAVI 的患者。

主要观察指标

引入 TAVI 服务前 2 年和引入后 2 年的主动脉瓣手术活动。传统主动脉瓣手术和 TAVI 的结果。

结果

在中心引入 TAVI 的 2 年内,与全国 8%的增长率相比,常规 AVR 活动增加了 37%(p<0.001)。与 TAVI 前的 2 年相比,逻辑 EuroSCORE 的平均值没有变化(7.4 比 7.9,p=0.16)或粗死亡率(2.9%比 2.1%,p=0.48)。50 例高危患者接受 TAVI,30 天死亡率为 0%。TAVI 患者的平均逻辑 EuroSCORE 为 25.3。

结论

TAVI 是高危患者 AVR 的一种新兴替代方法。自该中心引入 TAVI 服务以来,常规 AVR 活动增加。尽管平均逻辑 EuroSCORE 呈上升趋势,表明正在进行更复杂的病例,但粗死亡率没有显著降低。提供 TAVI 服务对常规 AVR 手术活动量有积极影响。

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