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[对若干人群中乙肝病毒流行率的回顾性研究]

[Retrospective review of the prevalence of hepatitis B virus in several population groups].

作者信息

Salom I, Román S, Macaya G, Fonseca J, Brenes F, Mora C, Martén A

机构信息

Unidad de Hepatologiá, Hospital México, Universidad de Costa Rica (UCR).

出版信息

Rev Biol Trop. 1990 Jun;38(1):83-6.

PMID:2093953
Abstract

Nine different groups of individuals studied from 1969 to 1985 were tested for Hepatitis B Virus (HBV) markers. In 8 groups only HBsAg in serum was tested, in another group: tissular HBsAg, and in two of those groups: serum HBsAg, anti-HBs and anti-HBc. Mean HBsAg prevalence in groups similar to general population was 0.64%; 5% in cirrhotics; HBV prevalence in haemophiliacs was 18.87% by testing serum for HBsAg and anti-HBs; serum HBsAg prevalence in Viral Chronic Active Hepatitis was 43.24%; and Hepatocellular Cancer (HCC) group had a prevalence for HBV of 13.04% when only tissular HBsAg was tested, and 54.29% when serum HBsAg, anti-HBs and anti-HBc were tested in all patients. Costa Rica has a low HBV markers prevalence only similar to what is found in industrial developed countries.

摘要

1969年至1985年期间对九组不同个体进行了乙肝病毒(HBV)标志物检测。八组仅检测血清中的HBsAg,另一组检测组织中的HBsAg,其中两组检测血清HBsAg、抗-HBs和抗-HBc。与普通人群相似的组中HBsAg平均流行率为0.64%;肝硬化患者中为5%;通过检测血清中的HBsAg和抗-HBs,血友病患者中的HBV流行率为18.87%;病毒性慢性活动性肝炎患者血清HBsAg流行率为43.24%;肝细胞癌(HCC)组仅检测组织中的HBsAg时HBV流行率为13.04%,对所有患者检测血清HBsAg、抗-HBs和抗-HBc时为54.29%。哥斯达黎加的HBV标志物流行率较低,仅与工业发达国家的情况相似。

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