Jánosi András, Ostör Erika, Borbás Sarolta, Kazinczy Rita, Káli András, Vámos István, Bradák Anna, Podmaniczky Márta
Fővárosi Önkormányzat Szent János Kórháza és Észak-budai Egyesített Kórházai III. Belgyógyászat-Kardiológia Budapest.
Orv Hetil. 2010 Oct 24;151(43):1776-82. doi: 10.1556/OH.2010.28961.
In year 1995 the European Society of Cardiology started an epidemiological study EUROASPIRE to evaluate the results of secondary prevention in some European countries. The first study period was in 1995, the second in 1999-2000 and the third in 2007. From Hungary the same study centers participated in EUROASPIRE I-II-III investigation. Authors present the Hungarian data and changes occurring the last ten years. During the three studies, 1627 coronary patients- younger than 70 years - were evaluated, using standardized methods. In the two Hungarian study centers, the proportion of women and patients older than 60 years increased. The hospital documentation of risk factors improved, at the time of EUROASPIRE III necessary data were found in 89%-99% of patient's records. Mean systolic and diastolic blood pressure continuously decreased between the first and second study period, but at the time of the third study 44% of the patients had elevated blood pressure (>140/90 mmHg). Prevalence of smoking decreased by 8% between second and third study period, however, at the time of the last study, 18% of coronary patients were smokers. The mean of total cholesterol was lower in the last study period comparing to the first investigation (5.6 vs. 5.2 mmol/l). HDL cholesterol level was unchanged and increasing triglyceride values were observed. During the study period the prevalence of obesity continuously increased from 23% to 49%. Prevalence of patients with total cholesterol level 5.5 mmol/l or higher has decreased from 60% to 24%, however 57% of patients did not reach the target level (4.5 mmol/l) although 80% of patients were treated with lipid lowering drugs: 76% of them received statins. Authors say that some part of secondary prevention improved during the last ten years, but many patients did not reach the target blood pressure and cholesterol level and it is embarrassing the prevalence of obesity and diabetes. The published data are not representative for whole Hungary; most probably the general situation is worse. Authors emphasize the importance of secondary prevention in the graduate and postgraduate education. For improving the secondary prevention, better cooperation is needed between hospital staff and patients and general practitioners as well.
1995年,欧洲心脏病学会启动了一项名为EUROASPIRE的流行病学研究,以评估一些欧洲国家二级预防的效果。第一个研究阶段是在1995年,第二个是在1999 - 2000年,第三个是在2007年。来自匈牙利的相同研究中心参与了EUROASPIRE I - II - III调查。作者展示了匈牙利的数据以及过去十年中发生的变化。在这三项研究中,使用标准化方法对1627名年龄小于70岁的冠心病患者进行了评估。在匈牙利的两个研究中心,女性和60岁以上患者的比例有所增加。危险因素的医院记录有所改善,在EUROASPIRE III时,89% - 99%的患者记录中找到了必要数据。在第一个和第二个研究阶段之间,平均收缩压和舒张压持续下降,但在第三个研究时,44%的患者血压升高(>140/90 mmHg)。在第二个和第三个研究阶段之间,吸烟率下降了8%,然而,在最后一项研究时,18%的冠心病患者仍在吸烟。与第一次调查相比,最后一个研究阶段的总胆固醇平均值较低(5.6 vs. 5.2 mmol/l)。高密度脂蛋白胆固醇水平未变,甘油三酯值有所上升。在研究期间,肥胖患病率从23%持续上升至49%。总胆固醇水平5.5 mmol/l或更高的患者患病率从60%降至24%,然而,57%的患者未达到目标水平(4.5 mmol/l),尽管80%的患者接受了降脂药物治疗:其中76%接受了他汀类药物治疗。作者表示,在过去十年中二级预防的某些方面有所改善,但许多患者未达到目标血压和胆固醇水平,肥胖和糖尿病的患病率令人尴尬。所公布的数据并不代表整个匈牙利的情况;很可能总体情况更糟。作者强调二级预防在研究生和研究生后教育中的重要性。为了改善二级预防,医院工作人员与患者以及全科医生之间需要更好的合作。