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[欧洲动脉粥样硬化调查-IV:欧洲心脏病学会关于冠状动脉疾病患者生活方式、危险因素及治疗方法的研究:来自土耳其的数据]

[EUROASPIRE-IV: European Society of Cardiology study of lifestyle, risk factors, and treatment approaches in patients with coronary artery disease: Data from Turkey].

作者信息

Tokgözoğlu Lale, Kayıkçıoğlu Meral, Altay Servet, Aydoğdu Sinan, Barçın Cem, Bostan Cem, Çakmak Hüseyin Altuğ, Çatakoğlu Alp Burak, Emet Samim, Ergene Oktay, Kalkan Ali Kemal, Kaya Barış, Tulunay Kaya Cansın, Kaymaz Cihangir, Koylan Nevrez, Kültürsay Hakan, Oğuz Aytekin, Özpelit Ebru, Ünlü Serkan

机构信息

Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.

出版信息

Turk Kardiyol Dern Ars. 2017 Mar;45(2):134-144. doi: 10.5543/tkda.2016.82352.

DOI:10.5543/tkda.2016.82352
PMID:28424435
Abstract

OBJECTIVE

Data from EUROASPIRE-IV Turkey report investigating risk factors and adherence to guidelines in patients hospitalized for coronary artery disease are presented and results are compared with those of EUROASPIRE-III Turkey and EUROASPIRE-IV Europe.

METHODS

Study was performed in 24 European countries, including Turkey (17 centers). Patients (18-80 years old) hospitalized for coronary (index) event during preceding 3 years were identified from hospital records and interviewed ≥6 months later. Patient information regarding index event was acquired from hospital records. Anamnesis was obtained during the interview, and physical examination and laboratory analyses were performed.

RESULTS

Median age at the index coronary event was 58.8 years, and it was significantly decreased compared with last EUROASPIRE-III study (60.5 years), which was conducted at the same centers 6 years earlier (p=0.017). Of all patients, 19.3% were under 50 years of age and mean age was lower than that of EUROASPIRE-IV Europe (62.5 years). Comparing EUROASPIRE-IV Turkey with EUROASPIRE-III Turkey, rate of smokers increased to 25.5% from 23.1% (p=0.499), obesity increased to 40.7% from 35.5% (p=0.211), total cholesterol level increased to 49.6% from 48.3% (p=0.767), and diabetes rate increased to 39.7% from 33.6% (p=0.139), however none of the differences reached a level of statistical significance. Only 11.7% of the smokers quit after coronary event. Rates for these factors were lower in EUROASPIRE-IV Europe (16% for smoking, 37.6% for obesity, and 26.8% for diabetes).

CONCLUSION

EUROASPIRE-IV Turkey data revealed that secondary prevention was unsatisfactory and had progressed unfavorably compared with last EUROASPIRE study, some risk factors were more uncontrolled than overall European average, and coronary artery events at young age remain an important problem.

摘要

目的

展示来自欧洲动脉粥样硬化预防调查-IV土耳其报告的数据,该报告调查了因冠状动脉疾病住院患者的危险因素及对指南的依从性,并将结果与欧洲动脉粥样硬化预防调查-III土耳其报告及欧洲动脉粥样硬化预防调查-IV欧洲报告的结果进行比较。

方法

研究在包括土耳其(17个中心)在内的24个欧洲国家开展。从医院记录中识别出在前3年因冠状动脉(索引)事件住院的患者(18 - 80岁),并在≥6个月后对其进行访谈。关于索引事件的患者信息从医院记录中获取。在访谈期间获取病史,并进行体格检查和实验室分析。

结果

索引冠状动脉事件发生时的中位年龄为58.8岁,与6年前在相同中心进行的上一次欧洲动脉粥样硬化预防调查-III研究(60.5岁)相比显著降低(p = 0.017)。在所有患者中,19.3%年龄在50岁以下,平均年龄低于欧洲动脉粥样硬化预防调查-IV欧洲报告中的患者(62.5岁)。将欧洲动脉粥样硬化预防调查-IV土耳其报告与欧洲动脉粥样硬化预防调查-III土耳其报告进行比较,吸烟者比例从23.1%增至25.5%(p = 0.499),肥胖者比例从35.5%增至40.7%(p = 0.211),总胆固醇水平从48.3%增至49.6%(p = 0.767),糖尿病患病率从33.6%增至39.7%(p = 0.139),然而这些差异均未达到统计学显著水平。冠状动脉事件后仅有11.7%的吸烟者戒烟。这些因素的比例在欧洲动脉粥样硬化预防调查-IV欧洲报告中更低(吸烟16%、肥胖37.6%、糖尿病26.8%)。

结论

欧洲动脉粥样硬化预防调查-IV土耳其报告的数据显示,二级预防情况不佳,与上一次欧洲动脉粥样硬化预防调查相比进展不利,一些危险因素的控制情况比欧洲总体平均水平更差,且年轻患者的冠状动脉事件仍是一个重要问题。

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