Centre for Eye Research Australia, University of Melbourne, East Melbourne, VIC, Australia.
Br J Ophthalmol. 2011 Jun;95(6):774-82. doi: 10.1136/bjo.2010.191312. Epub 2010 Oct 12.
Understanding the impact of a condition from the patient's perspective is important, and different types of patient-reported outcomes or instruments are available to help with this. This review article summarises the current evidence on the impact of diabetic retinopathy (DR) and its associated vision impairment on patient-reported outcomes. We have included research that has used a range of outcome measures to assess the impact of DR on generic health-related quality of life, utility, vision-functioning and vision-specific quality of life. This review also offers clarification on frequently misused psychometric terminologies to help clinicians and researchers better understand the literature associated with patient-reported outcome research. Overall, the evidence suggests that DR, particularly in its vision-threatening stages, has a substantial, negative impact on the patient. However, our understanding of the impact of DR is currently restricted due to limitations inherent in currently available patient-reported outcome measures. We conclude by discussing potential directions for future research in this area, such as item banking and computer adaptive testing.
从患者角度了解疾病的影响很重要，为此有多种类型的患者报告结局或工具可供使用。本文综述了目前关于糖尿病视网膜病变（DR）及其相关视力损害对患者报告结局影响的证据。我们纳入了使用各种结局指标评估 DR 对一般健康相关生活质量、效用、视力功能和视力特异性生活质量影响的研究。本文还对经常被误用的心理计量学术语进行了澄清，以帮助临床医生和研究人员更好地理解与患者报告结局研究相关的文献。总体而言，证据表明，DR 特别是在其威胁视力的阶段，对患者有实质性的负面影响。然而，由于目前可用的患者报告结局测量工具固有的限制，我们对 DR 影响的理解目前还很有限。最后，我们讨论了该领域未来研究的潜在方向，如项目库和计算机自适应测试。
