Kormos C, Köteles G J
Frédéric Joliot-Curie, National Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary.
Acta Biol Hung. 1990;41(1-3):115-20.
The frequencies of chromosome aberrations induced by ionizing radiations were studied for use in assessment of doses in radiation accidents. The dose-effect relationships of formations of dicentric and acentric aberrations are compared with that of micronuclei detected in cultured human lymphocytes. The data suggest the applicability of micronucleus test as "biological dosimeter" with a similar sensitivity like the widely used dicentric analysis.
研究了电离辐射诱导的染色体畸变频率，以用于辐射事故中的剂量评估。将双着丝粒和无着丝粒畸变形成的剂量效应关系与在培养的人类淋巴细胞中检测到的微核的剂量效应关系进行了比较。数据表明微核试验作为“生物剂量计”具有适用性，其灵敏度与广泛使用的双着丝粒分析相似。
