Hamburger H L, Triantafyllou N I
Department of Clinical Neurophysiology, Municipal Hospital Slotervaart, Amsterdam, The Netherlands.
Brain Topogr. 1990 Fall;3(1):49-52. doi: 10.1007/BF01128861.
Auditory ERP (AERP) studies have been performed in 56 patients with central nervous system disturbances. Forty seven patients (90.5%), had AERP component abnormalities concerning mainly P300 topography alterations and secondarily P300 latency prolongation. It is concluded that P300 is a very useful tool in clinical neurology and that P300 topography or latency alterations are not specific of any cerebral disturbance but can be found in any disease whenever cognitive functions are impaired.