Rose Randy L
North Carolina State University, Raleigh, North Carolina, USA.
Curr Protoc Toxicol. 2002 Nov;Chapter 4:Unit4.9. doi: 10.1002/0471140856.tx0409s13.
Measurement of Flavin-Containing Monooxygenase (FMO) Activities (Randy L. Rose, North Carolina State University, Raleigh, North Carolina). This unit describes methods used for measuring the presence of flavin-containing monooxygenases using NADPH oxygenation and methamizole oxidation. Methods are also provided to determine the relative contributions of FMO versus cytochrome P450 from microsomes.
含黄素单加氧酶(FMO)活性的测定(兰迪·L·罗斯,北卡罗来纳州立大学,罗利,北卡罗来纳州)。本单元描述了利用NADPH氧化和甲巯咪唑氧化来测定含黄素单加氧酶存在的方法。还提供了确定微粒体中FMO与细胞色素P450相对贡献的方法。