C-H 键功能化在稠合 1,2,3-三唑合成中的应用。
C-H bond functionalization in the synthesis of fused 1,2,3-triazoles.
机构信息
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, M5S 3H6, Canada.
出版信息
Org Lett. 2010 Nov 19;12(22):5092-5. doi: 10.1021/ol102342y. Epub 2010 Oct 14.
PMID:20945894
Abstract
A highly modular approach to fused 1,2,3-triazoles has been developed featuring a one-pot procedure combining copper(I) catalyzed azide-alkyne cycloaddition and palladium-catalyzed C-H bond functionalization. A class of structurally unique heterocycles was synthesized in good yields.
摘要
发展了一种高度模块化的融合 1,2,3-三唑的方法，其特征在于一锅法结合铜（I）催化的叠氮-炔环加成和钯催化的 C-H 键官能化。以良好的收率合成了一类结构独特的杂环。
Zotero 插件