Hollingdale M R
Biomedical Research Institute, Rockville, MD 20852.
Bull World Health Organ. 1990;68 Suppl(Suppl):47-51.
Development of anti-sporozoite vaccines based on CS (circumsporozoite) proteins has preceded a thorough understanding of the basic biology of sporozoite-hepatic cell interactions. Investigation of these interactions can only serve to further refine the existing sporozoite vaccines, as well as provide a rationale for the design of other vaccine candidates.
基于环子孢子蛋白(CS)开发抗子孢子疫苗之前,人们尚未深入了解子孢子与肝细胞相互作用的基础生物学。对这些相互作用的研究不仅有助于进一步优化现有的子孢子疫苗,还能为设计其他候选疫苗提供理论依据。