Centre for Therapeutic Endoscopy and Endoscopic Oncology, St. Michael's Hospital, Toronto, Canada.
Dis Esophagus. 2011 May;24(4):211-4. doi: 10.1111/j.1442-2050.2010.01120.x. Epub 2010 Oct 13.
Esophageal lichen planus is a rare condition, and although the majority of cases occur in conjunction with lichen planus at other sites, the endoscopic features are often misinterpreted resulting in a delay in diagnosis. We report a series of five patients presenting to our unit between 2005 and 2009. All five patients were female and presented with dysphagia. Endoscopy demonstrated proximal esophageal stricturing in four patients. Characteristic histological findings were found in four patients. Lichen planus was diagnosed at other sites, and preceded gastrointestinal symptoms, in all patients; five had oral involvement, two had genital involvement, and one had dermal involvement. All patients received proton pump inhibitor therapy without demonstrable benefit. Administration of oral fluticasone proprionate resulted in symptomatic improvement in three patients.
食管扁平苔藓是一种罕见的疾病，尽管大多数病例与其他部位的扁平苔藓同时发生，但内镜下的特征常被误解，导致诊断延误。我们报告了一组 5 例患者，他们于 2005 年至 2009 年期间在我们科室就诊。这 5 例患者均为女性，表现为吞咽困难。内镜检查显示 4 例患者存在近端食管狭窄。4 例患者均发现有特征性的组织学表现。所有患者均在其他部位诊断为扁平苔藓，且胃肠道症状均先于扁平苔藓出现；5 例患者口腔受累，2 例患者生殖器受累，1 例患者皮肤受累。所有患者均接受质子泵抑制剂治疗，但未见明显疗效。3 例患者口服丙酸氟替卡松后症状改善。
