Department of Oral & Maxillofacial Surgery, School of Dentistry, Damascus University, Damascus, Syria.
Clin Oral Implants Res. 2011 Mar;22(3):265-74. doi: 10.1111/j.1600-0501.2010.01990.x. Epub 2010 Oct 13.
The aim of this pilot study was to compare the early-term osseointegration characteristics of standard (SLA) and modified sand-blasted and acid-etched (modSLA) implants in an experimental animal model.
A total of 30 SLA and modSLA implants were placed to the tibiae of three sheep and the insertion torque value (ITV) and resonance frequency analysis (RFA) measurements were performed. RFA measurement was repeated on 3 and 6 weeks healed implants after which the animals were sacrificed for histomorphometric analysis. Bone-to-implant contact was assessed on the non-decalcified sections. Six weeks healed implants were also subjected to the reverse torque test (RTT). Results were analyzed by the Friedman test, Kruskal-Wallis test and Spearman rank correlation test.
All implants reached to a strong primary stability with a mean 36.13 ± 2.47 and 35.47 ± 2.85 N/cm ITV. In the surgical stage, RFA values for SLA and modSLA implants were found to be 72.27 ± 3.17 and 71.6 ± 2.87, respectively. After 3 weeks of healing, mean BIC% (80.64 ± 13.89%) and RFA value (76.8 ± 1.14) of modSLA implants were significantly higher (P=0.0002) than that of SLA implants (64.39 ± 21.2 BIC% and 74.2 ± 4.76 RFA). However, no statistically significant difference between SLA and modSLA implants was recorded after 6 weeks of healing. Both implants revealed similar results in the RTT test (115.2 ± 4.14 and 117 ± 4.47 N/cm for SLA and modSLA implants, respectively). No correlation was found between RFA and BIC%.
Within the limits of this pilot study, it can be concluded that modSLA implants achieve a higher bone contact and stability at earlier time points when compared with SLA implants.
本初步研究旨在比较标准（SLA）和改良喷砂酸蚀（modSLA）种植体在实验动物模型中的早期骨整合特征。
将 30 个 SLA 和 modSLA 种植体植入 3 只绵羊的胫骨中，分别进行植入扭矩值（ITV）和共振频率分析（RFA）测量。在愈合 3 周和 6 周后，重复进行 RFA 测量，然后处死动物进行组织形态学分析。在非脱钙切片上评估骨与种植体的接触情况。将愈合 6 周的种植体也进行反转扭矩试验（RTT）。采用 Friedman 检验、Kruskal-Wallis 检验和 Spearman 秩相关检验对结果进行分析。
所有种植体均达到了很强的初始稳定性，平均植入扭矩值分别为 36.13 ± 2.47 N/cm 和 35.47 ± 2.85 N/cm。在手术阶段，SLA 和 modSLA 种植体的 RFA 值分别为 72.27 ± 3.17 和 71.6 ± 2.87。愈合 3 周后，modSLA 种植体的平均骨结合百分比（80.64 ± 13.89%）和 RFA 值（76.8 ± 1.14）显著高于 SLA 种植体（64.39 ± 21.2%和 74.2 ± 4.76 RFA）（P=0.0002）。然而，在愈合 6 周后，SLA 和 modSLA 种植体之间没有统计学上的显著差异。在 RTT 试验中，两种种植体均表现出相似的结果（SLA 和 modSLA 种植体的 RTT 值分别为 115.2 ± 4.14 N/cm 和 117 ± 4.47 N/cm）。RFA 值与骨结合百分比之间没有相关性。
在本初步研究的范围内，可以得出结论，与 SLA 种植体相比，modSLA 种植体在更早的时间点获得了更高的骨接触和稳定性。
