School of Dentistry, Universidade Federal de Santa Catarina, Florianopolis, Brazil.
Clin Implant Dent Relat Res. 2011 Jun;13(2):87-94. doi: 10.1111/j.1708-8208.2009.00186.x.
Thin bioceramic coatings have been regarded as potential substitutes for plasma-sprayed hydroxyapatite coatings.
This study tested the hypothesis that a thin bioactive ceramic coating deposition on an alumina-blasted/acid-etched (AB/AE) surface would positively affect the biomechanical fixation and bone-to-implant contact (BIC) of plateau root form implants.
Implants of two different lengths (i.e., 4.5 × 11 mm long, n = 36) and 4.5 × 6 mm (short, n = 36) and two different surfaces, that is, control (AB/AE) and test (AB/AE + 300 - 500 nm bioactive ceramic coating), were placed in the proximal tibiae of six beagle dogs. The implants were retrieved for analyses 2 and 4 weeks after placement. The implants in bone specimens were subjected to torque loads until a 10% drop of the maximum torque was recorded. The specimens were evaluated under optical microscopy for bone morphology and percent BIC. Statistical analysis was performed by a generalized linear mixed effects analysis of variance model and statistical significance set at p < 0.05.
Significantly higher torque-to-interface fracture levels for test surface groups of both lengths when compared to control surfaces were observed. No significant difference in BIC was observed between test and control implants of equal length. Histomorphological analysis showed higher degrees of bone organization between the plateaus of test implant surfaces at both implantation times.
Because the presence of a thin bioactive ceramic coating on the surface did not affect BIC, but positively affected implant biomechanical fixation, the hypothesis was partially validated.
薄型生物陶瓷涂层已被视为等离子喷涂羟基磷灰石涂层的潜在替代品。
本研究检验了以下假设，即在喷砂酸蚀（AB/AE）表面上沉积薄的生物活性陶瓷涂层会积极影响高原根形式植入物的生物力学固定和骨与植入物接触（BIC）。
两种不同长度（即 4.5×11mm 长，n=36 和 4.5×6mm 短，n=36）和两种不同表面的植入物，即对照（AB/AE）和试验（AB/AE+300-500nm 生物活性陶瓷涂层），被植入 6 只比格犬的胫骨近端。植入物在植入后 2 周和 4 周进行回收分析。将骨标本中的植入物置于扭矩负载下，直至记录到最大扭矩下降 10%。在光学显微镜下评估标本的骨形态和 BIC 百分比。通过广义线性混合效应方差分析模型进行统计分析，统计显著性设为 p<0.05。
与对照表面相比，两种长度的试验表面组的界面断裂扭矩水平明显更高。等长的试验和对照植入物的 BIC 无显著差异。组织形态学分析显示，在两个植入时间，试验植入物表面的平台之间存在更高程度的骨组织。
由于表面存在薄的生物活性陶瓷涂层不会影响 BIC，但会积极影响植入物的生物力学固定，因此该假设得到了部分验证。
