Department of Crystallography, Institute of Structural and Molecular Biology, Birkbeck College, University of London, London WC1E 7HX, UK.
Structure. 2010 Oct 13;18(10):1267-9. doi: 10.1016/j.str.2010.08.008.
The Protein Circular Dichroism Data Bank (PCDDB) is a newly released resource for structural biology. It is a web-accessible (http://pcddb.cryst.bbk.ac.uk) data bank for circular dichroism (CD) and synchrotron radiation circular dichroism (SRCD) spectra and their associated experimental and secondary metadata, with links to protein sequence and structure data banks. It is designed to provide a public repository for CD spectroscopic data on macromolecules, to parallel the Protein Data Bank (PDB) for crystallographic, electron microscopic, and nuclear magnetic resonance spectroscopic data. Similarly to the PDB, it includes validation checking procedures to ensure good practice and the integrity of the deposited data. This paper reports on the first public release of the PCDDB, which provides access to spectral data that comprise standard reference datasets.
蛋白质圆二色性数据库(PCDDB)是一个新发布的结构生物学资源。它是一个可通过网络访问的数据库(http://pcddb.cryst.bbk.ac.uk),用于存储圆二色性(CD)和同步辐射圆二色性(SRCD)光谱以及与其相关的实验和二级元数据,并与蛋白质序列和结构数据库建立了链接。它旨在为大分子的 CD 光谱数据提供一个公共存储库,以与蛋白质数据银行(PDB)平行,用于晶体学、电子显微镜和核磁共振光谱数据。与 PDB 类似,它包括验证检查程序,以确保良好的实践和所存储数据的完整性。本文报告了 PCDDB 的首次公开版本,它提供了对构成标准参考数据集的光谱数据的访问。