Department of General Microbiology, Georg-August University Göttingen, Grisebachstr. 8, 37077 Göttingen, Germany.
Bioinformatics. 2010 Dec 1;26(23):2997-9. doi: 10.1093/bioinformatics/btq585. Epub 2010 Oct 14.
Systems biology relies increasingly on collaborations between several groups with different expertise. Therefore, the systems biology community is adopting standards that allow effective communication of concepts, as well as transmission and processing of pathway information. The Systems Biology Graphical Notation (SBGN) is a graphical language for biological pathways that has both a biological as well as a computational meaning. The program CellDesigner allows the codification of biological phenomena in an SBGN compliant form. CellPublisher is a web server that allows the conversion of CellDesigner files to web-based navigatable diagrams based on the user interface of Google maps. Thus, CellPublisher complements CellDesigner by facilitating the understanding of complex diagrams and by providing the possibility to share any CellDesigner diagram online with collaborators and get their feedback. Due to the intuitive interface of the online diagrams, CellPublisher serves as a basis for discovery of novel properties of the modelled networks.
The freely available web server and the documentation can be accessed at: http://cellpublisher.gobics.de/. The source code and the offline version for Microsoft Windows are freely available at http://sourceforge.net/projects/cellpublisher/.
Supplementary data are available at Bioinformatics online.
系统生物学越来越依赖于具有不同专业知识的多个团队之间的合作。因此，系统生物学界正在采用允许有效传达概念以及传输和处理途径信息的标准。系统生物学图形符号 (SBGN) 是一种用于生物途径的图形语言，具有生物学和计算意义。CellDesigner 程序允许以符合 SBGN 的形式对生物现象进行编码。CellPublisher 是一个 Web 服务器，允许根据 Google 地图的用户界面将 CellDesigner 文件转换为基于 Web 的可导航图。因此，CellPublisher 通过方便理解复杂的图并提供与合作者在线共享任何 CellDesigner 图并获得他们的反馈来补充 CellDesigner。由于在线图的直观界面，CellPublisher 可作为发现所建模网络的新特性的基础。
免费的 Web 服务器和文档可在以下网址获得：http://cellpublisher.gobics.de/。适用于 Microsoft Windows 的源代码和离线版本可在以下网址免费获得：http://sourceforge.net/projects/cellpublisher/。
补充数据可在 Bioinformatics 在线获得。
