IgE反应的调节
Regulation of the IgE response.
作者信息
Conrad Daniel H, Gibb David R, Sturgill Jamie
机构信息
Department of Microbiology and Immunology, Virginia Commonwealth University Box 980678, Richmond, VA 23298 USA.
出版信息
F1000 Biol Rep. 2010 Feb 24;2:14. doi: 10.3410/B2-14.
Abstract
IgE was the last of the five immunoglobulin classes to be discovered and is the antibody that is responsible for much of human type I allergic disease. This review summarizes recent developments with respect to control of IgE synthesis with an emphasis on Th2 (T helper 2) control and regulation using IgE Fc receptors.
摘要
免疫球蛋白E（IgE）是最后发现的五类免疫球蛋白之一，是引发人类大部分I型过敏疾病的抗体。本综述总结了关于控制IgE合成的最新进展，重点是利用IgE Fc受体对辅助性T细胞2（Th2）的控制和调节。
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