Liebeskind David S
University of California at Los Angeles Stroke Center 710 Westwood Plaza, Los Angeles, CA 90095 USA.
F1000 Med Rep. 2010 Sep 23;2:71. doi: 10.3410/M2-71.
Revascularization remains the most intuitive strategy to reverse ischemic injury associated with arterial occlusion in acute stroke. Revascularization may lead to opening of an occluded artery, or recanalization, yet restoration of downstream flow, or reperfusion, may not ensue. Revascularization strategies and novel devices continue to broaden options for the treatment of acute stroke, but it is increasingly apparent that selection criteria to identify ideal cases are needed to refine triage and minimize adverse events. The results of recent work on reperfusion may rapidly alter routine clinical practice for evolving ischemia in the brain.
血管再通仍然是逆转急性卒中动脉闭塞相关缺血性损伤最直观的策略。血管再通可能导致闭塞动脉开放，即再通，但下游血流恢复，即再灌注，可能不会随之发生。血管再通策略和新型设备不断拓宽急性卒中的治疗选择，但越来越明显的是，需要确定理想病例的选择标准，以优化分诊并尽量减少不良事件。近期关于再灌注的研究结果可能会迅速改变针对脑部进行性缺血的常规临床实践。
