Dickie Laura J, Savic Sinisa, Aziz Azad, Sprakes Michael, McDermott Michael F
NIHR-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU), Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, St. James's University Hospital Leeds, LS9 7TF UK.
F1000 Med Rep. 2010 Jan 18;2:3. doi: 10.3410/M2-3.
The concept of autoinflammatory disease as a new disease classification has resulted in a paradigm shift in our understanding of the the broad spectrum of immunological diseases. The effectiveness of interleukin-1 blockade in a variety of disorders has resulted in a marked reduction in suffering for many of these patients.
自身炎症性疾病作为一种新的疾病分类概念,已使我们对广泛的免疫性疾病的理解发生了范式转变。白细胞介素-1阻断在多种疾病中的有效性已使许多此类患者的痛苦显著减轻。