Nüllen H, Noppeney T
Gemeinschaftspraxis für Gefässmedizin in Mönchengladbach, Deutschland.
Chirurg. 2010 Nov;81(11):1035-44; quiz 1045. doi: 10.1007/s00104-009-1865-y.
This is the first of two articles on the diagnosis and treatment of varicose veins. Primary varicosis is a congenital degenerative disease of the peripheral venous system of the lower extremities. The realisation factors are age, female sex and pregnancy. Degeneration of the peripheral veins leads to dilatation of the lumen and insufficient closure of the valves resulting in a backflow of blood from deep to the superficial venous system. This leads to ambulatory hypertension in the superficial venous system and recirculation of noteworthy amounts of venous drainage blood in the affected leg. Without treatment this results in the long term in variable degrees of decompensation of the recirculation pathways and an increasing (volume-induced) secondary insufficiency of the deep venous system. The result corresponds to the clinical symptoms of chronic venous insufficiency (CVI). When treatment is started early enough the pathological course can be reduced or avoided. The various therapeutic measures will be described in the second article of this series.
这是关于静脉曲张诊断与治疗的两篇文章中的第一篇。原发性静脉曲张是下肢外周静脉系统的一种先天性退行性疾病。发病相关因素包括年龄、女性性别和妊娠。外周静脉退化导致管腔扩张以及瓣膜关闭不全,从而使血液从深静脉系统反流至浅静脉系统。这会导致浅静脉系统出现动态高血压,并使患侧腿部有大量静脉回流血液发生再循环。若不进行治疗,长期会导致再循环路径不同程度的失代偿,以及深静脉系统继发性(容量性)功能不全加重。其结果与慢性静脉功能不全(CVI)的临床症状相符。若尽早开始治疗,可减轻或避免疾病的病理进程。本系列第二篇文章将描述各种治疗措施。