Urogynaecology, Department of Obstetrics and Gynaecology, University of Bern and University Hospital, Bern, Switzerland.
Neurourol Urodyn. 2011 Mar;30(3):325-8. doi: 10.1002/nau.20997. Epub 2010 Oct 14.
Measurement of bladder wall thickness (BWT) using transvaginal ultrasound has previously been shown to discriminate between women with confirmed detrusor overactivity and those with urodynamic stress incontinence. Aim of the current study was to determine if vaginally measured BWT correlates with urodynamic diagnoses in a female population.
Between December 2008 and February 2010, adult female consecutive patients undergoing urogynaecologic investigation for lower urinary symptoms were approached to participate in this study. Ethical consent for the current study was obtained. Patients underwent multichannel urodynamics and transvaginal ultrasound measuring the bladder in three location with an emptied bladder.
123 patients were included in the study with a median age of 69 years (range 40-93), median parity of 2 (range 0-3) and a median body mass index of 29.5 kg/m(2) (range 23-38). Urodynamic stress incontinence was diagnosed in 59 patients, DO in 40 and obstruction in 24 cases. Bladder wall thickness was significantly higher in DO patients and in obstruction than in urodynamic stress incontinence. Detrusor pressure at maximum flow rate (pdet/Q(max) ) correlated significantly with BWT.
Bladder wall thickness shows a significantly positive correlation to pdet/Q(max) and to urodynamic diagnoses of stress incontinence, DO and obstruction.
经阴道超声测量膀胱壁厚度（BWT）以前被证明可以区分逼尿肌过度活动和尿动力学压力性尿失禁的女性。本研究的目的是确定女性人群中经阴道测量的 BWT 是否与尿动力学诊断相关。
在 2008 年 12 月至 2010 年 2 月期间，对因下尿路症状接受妇科泌尿科检查的成年女性连续患者进行了这项研究。目前的研究获得了伦理同意。患者接受了多通道尿动力学检查和经阴道超声检查，在排空膀胱的情况下，在三个位置测量膀胱。
123 例患者纳入本研究，年龄中位数为 69 岁（范围 40-93），产次中位数为 2（范围 0-3），体重指数中位数为 29.5kg/m2（范围 23-38）。59 例患者诊断为尿动力学压力性尿失禁，40 例为逼尿肌过度活动，24 例为梗阻。逼尿肌过度活动和梗阻患者的膀胱壁厚度明显高于尿动力学压力性尿失禁患者。最大尿流率时逼尿肌压力（pdet/Q(max)）与 BWT 显著相关。
膀胱壁厚度与 pdet/Q(max) 以及尿动力学诊断的压力性尿失禁、逼尿肌过度活动和梗阻呈显著正相关。
