Serati Maurizio, Salvatore Stefano, Cattoni Elena, Soligo Marco, Cromi Antonella, Ghezzi Fabio
Dept of Obstetrics and Gynecology, University of Insubria, Del Ponte Hospital, Piazza Biroldi 1, Varese 21100, Italy.
Int Urogynecol J. 2010 Nov;21(11):1405-11. doi: 10.1007/s00192-010-1194-1. Epub 2010 Jun 10.
Aims of this study were to compare the ultrasound measurement of bladder wall thickness (BWT) in women with different urodynamic diagnosis and to correlate BWT to the different urodynamic findings of detrusor overactivity (DO).
Two hundred forty seven women with urinary symptoms have been prospectively enrolled. Urodynamics and transvaginal ultrasound BWT were performed. Patients were divided into four urodynamic subgroups. BWT of women with DO was compared with the BWT of any other subgroup.
Women with DO had a BWT value significantly higher (p < 0.0001). A cut-off of 6.5 mm for BWT had a positive predictive value of 100% for all DO. We use ROC curves to analyze the BWT for urgency urinary incontinence (AUC 0.645 95% CI 0.57-0.72) and the BWT for "pure DO" (AUC 0.702 95% CI 0.64-0.76) and for "all DO" (AUC 0.704 95% CI 0.64-0.77) vs other urodynamic diagnoses.
The ultrasound BWT showed a highly significant association with DO. However, the performance of this test cannot currently replace urodynamic testing.
本研究的目的是比较不同尿动力学诊断的女性膀胱壁厚度（BWT）的超声测量值，并将BWT与逼尿肌过度活动（DO）的不同尿动力学结果相关联。
前瞻性纳入了247名有泌尿系统症状的女性。进行了尿动力学检查和经阴道超声测量BWT。患者被分为四个尿动力学亚组。将患有DO的女性的BWT与其他任何亚组的BWT进行比较。
患有DO的女性的BWT值显著更高（p < 0.0001）。BWT的截断值为6.5 mm时，对所有DO的阳性预测值为100%。我们使用ROC曲线分析了尿急尿失禁的BWT（AUC 0.645，95% CI 0.57 - 0.72）、“单纯DO”的BWT（AUC 0.702，95% CI 0.64 - 0.76）以及“所有DO”的BWT（AUC 0.704，95% CI 0.64 - 0.77）与其他尿动力学诊断的对比情况。
超声测量的BWT与DO显示出高度显著的相关性。然而，目前该检查的性能尚不能替代尿动力学检查。
