Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy.
Respir Med. 2011 Mar;105(3):386-91. doi: 10.1016/j.rmed.2010.09.022. Epub 2010 Oct 15.
We conducted a population-based cross-sectional epidemiologic survey of asthma and COPD in an adult representative national sample using information obtained from the Health Search Database owned by the Italian College of General Practitioners. General Practitioners who had a list of patient population of 909,638 individuals (429,962 men and 479,676 women; man/woman ratio [M/WR]: 0.89) ≥ 14 years old at the end of December 2009 were selected to be representatives of the whole Italian population. Cases of asthma and COPD were identified on the basis of the ICD-9 codes. The total sample included 55,500 (6.10% of the entire population; 5.49% of men and 6.64% of women; M/WR: 0.74) subjects suffering from asthma and 25,762 (2.83% of the entire population; 3.51% of men and 2.23% of women; M/WR: 1.41) subjects suffering from COPD. The asthma/COPD ratio in general population was 2.16. The odds ratio (OR) was chosen because asthma and COPD had a prevalence less than 10%. The OR of developing asthma decreased with age both in men and women, but in the first group of age (15-34 years) it was higher in men vs. women (1.69 vs. 1.00) although it became lower than 1 from 35 years old and up in men and from 75 years old and up in women. On the contrary, the OR of developing COPD became higher than 1 from 55 years old and up both in men and in women and progressively increased with age (in the group 75-84 years, it was 6.16 in men and 4.07 in women, respectively).
我们使用意大利全科医生学院拥有的健康搜索数据库中的信息，对成年人代表性全国样本进行了哮喘和 COPD 的基于人群的横断面流行病学调查。选择在 2009 年 12 月底拥有 909638 名患者（429962 名男性和 479676 名女性；男女比例 [M/WR]：0.89）≥14 岁的全科医生作为意大利全体人口的代表。根据 ICD-9 编码确定哮喘和 COPD 的病例。总样本包括 55500 名（占总人口的 6.10%；男性占 5.49%，女性占 6.64%；M/WR：0.74）患有哮喘的患者和 25762 名（占总人口的 2.83%；男性占 3.51%，女性占 2.23%；M/WR：1.41）患有 COPD 的患者。普通人群中哮喘/COPD 的比例为 2.16。选择比值比（OR）是因为哮喘和 COPD 的患病率低于 10%。无论男女，哮喘的发病 OR 均随年龄增长而降低，但在第一组年龄（15-34 岁）中，男性高于女性（1.69 比 1.00），但从 35 岁及以上的男性和 75 岁及以上的女性开始，该比值低于 1。相反，无论男女，COPD 的发病 OR 从 55 岁及以上开始均高于 1，且随年龄增长而逐渐增加（在 75-84 岁组中，男性为 6.16，女性为 4.07）。
