University of Pennsylvania School of Medicine, Suite 100, Stemmler Hall, 3450 Hamilton Walk, Philadelphia, PA 19104, USA.
Gastroenterol Clin North Am. 2010 Sep;39(3):559-99. doi: 10.1016/j.gtc.2010.08.011.
Mesalamine has been the first-line of therapy in patients with inflammatory bowel disease (IBD) since the 1960s. This article serves as a review of the different 5-aminosalicylic acid compounds, release formulations, use and dosing in the treatment of IBD, in particular ulcerative colitis.
美沙拉嗪自 20 世纪 60 年代以来一直是炎症性肠病(IBD)患者的一线治疗药物。本文旨在回顾不同的 5-氨基水杨酸化合物、释放制剂、在治疗 IBD(尤其是溃疡性结肠炎)中的用途和剂量。