Hanauer S B
University of Chicago Medical Center, Illinois 60637.
Neth J Med. 1989 Jun;35 Suppl 1:S11-20.
5-Aminosalicylic acid (5-ASA) enema therapy has been a direct extension of our understanding of the pharmacology and metabolism of sulfasalazine. Clinical studies have documented the efficacy and safety of topical 5-ASA therapy in distal ulcerative colitis. Future clinical experience should clarify the role of topical 5-ASA in a variety of inflammatory bowel disease syndromes.
5-氨基水杨酸（5-ASA）灌肠疗法是我们对柳氮磺胺吡啶药理学和代谢认识的直接延伸。临床研究已证明局部应用5-ASA治疗远端溃疡性结肠炎的有效性和安全性。未来的临床经验应能阐明局部应用5-ASA在各种炎症性肠病综合征中的作用。
