Vlaicu R, Popescu E, Popescu T A, Cucuianu M
Endocrinologie. 1978 Apr-Jun;16(2):147-51.
Decreased levels of serum cholesterol and beta-lipoproteins occurring in hyperthyroidism were found to be accompanied by an enchanced activity of pseudocholinesterase, while in patients with myxedema, the pathologically increased levels of serum cholesterol and beta-lipoproteins were associated with diminished serum pseudocholinesterase activity. The percentage of the pre-beta fraction was found to be increased in both hypo- and hyperthyroid patients, but mechanisms leading to this change are probably different in the two pathological conditions. The behaviour of cholesterol and pseudocholinesterase activity and especially the ratio between these paramameters might be used for the diagnosis of thyroid disease and for the control of therapeutic efficiency.
甲状腺功能亢进症患者血清胆固醇和β-脂蛋白水平降低，同时假性胆碱酯酶活性增强；而黏液性水肿患者血清胆固醇和β-脂蛋白水平病理性升高，血清假性胆碱酯酶活性降低。甲状腺功能减退和亢进患者的前β组分百分比均升高，但导致这种变化的机制在两种病理状态下可能不同。胆固醇和假性胆碱酯酶活性的变化，尤其是这些参数之间的比值，可用于甲状腺疾病的诊断和治疗效果的监测。
