采用雾化吸入布地奈德“局部”治疗食管克罗恩病。
Esophageal Crohn's disease treated "topically" with swallowed aerosolized budesonide.
作者信息
Zezos Petros, Kouklakis Georgios, Oikonomou Anastasia, Pitiakoudis Michail, Simopoulos Constantinos
机构信息
Gastrointestinal Endoscopy Unit, University General Hospital of Alexandroupolis, Democritus University of Thrace, Dragana, 68100 Alexandroupolis, Greece.
出版信息
Case Rep Med. 2010;2010. doi: 10.1155/2010/418769. Epub 2010 Sep 30.
Proximal Crohn's disease, involving the esophagus, the stomach, the duodenum, and the proximal jejunum, is uncommon. Treatment for proximal Crohn's disease is based on data derived from case series than from controlled trials. We present a case of Crohn's colitis with concomitant proximal esophagogastroduodenal involvement treated with conventional treatment plus swallowed aerosolized budesonide as a novel adjuvant topical treatment for the esophageal disease, and we review the treatment options for proximal Crohn's disease.
累及食管、胃、十二指肠和空肠近端的近端克罗恩病并不常见。近端克罗恩病的治疗依据来自病例系列的数据，而非对照试验。我们报告一例克罗恩结肠炎合并近端食管胃十二指肠受累的病例，采用传统治疗加吞咽雾化布地奈德作为食管疾病的新型辅助局部治疗，并回顾近端克罗恩病的治疗选择。
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