Division of Allergy, Immune and Respiratory System, Department of Internal Medicine, College of Oriental Medicine, Kyung Hee University, Seoul 130-702, Republic of Korea.
Evid Based Complement Alternat Med. 2011;2011. doi: 10.1155/2011/678176. Epub 2010 Sep 16.
Pharmacopuncture is a new needle therapy that integrates acupuncture and herbal therapies, and it has the potential to treat many diseases. A systematic review was performed to summarize and critically evaluate clinical trial evidence regarding the effectiveness of pharmacopuncture for asthma. Eight electronic databases and six journals were searched in this study. Randomized clinical trials (RCTs) in which human patients with asthma were treated with pharmacopuncture were included. The selection of studies, data extraction, and validation were performed independently by two reviewers. Four RCTs met our inclusion criteria, and the evidence from all RCTs in this study was positive. The meta-analysis showed statistically significant effects of pharmacopuncture compared to conventional treatment (n = 341, Risk Ratio = 1.13, 95% CI of 1.05 to 1.23, P = .002, heterogeneity: χ(2) = 3.55, P = .31, I(2) = 16%). Two trials showed favorable effects of pharmacopuncture on peak expiratory flow (PEF). However, few rigorous trials have tested the effects of pharmacopuncture on asthma. The results of our systematic review point to the potential benefits of pharmacopuncture for adults with asthma, and we suggest further RCTs and the development of a standard method of pharmacopuncture therapy.
穴位药物注射疗法是一种将针刺与草药疗法相结合的新型针刺疗法，具有治疗多种疾病的潜力。本研究进行了系统评价，以总结和批判性评估穴位药物注射疗法治疗哮喘的临床疗效的临床试验证据。本研究共检索了 8 个电子数据库和 6 种期刊。纳入了穴位药物注射疗法治疗哮喘的人类患者的随机临床试验（RCT）。研究选择、数据提取和验证由两位评审员独立进行。有 4 项 RCT 符合我们的纳入标准，本研究中所有 RCT 的证据均为阳性。荟萃分析显示，与常规治疗相比，穴位药物注射疗法具有统计学显著效果（n = 341，风险比 = 1.13，95%置信区间为 1.05 至 1.23，P =.002，异质性：χ(2) = 3.55，P =.31，I(2) = 16%）。有两项试验显示穴位药物注射疗法对呼气峰流速（PEF）有有利影响。然而，很少有严格的试验测试过穴位药物注射疗法对哮喘的影响。我们的系统评价结果表明穴位药物注射疗法对成人哮喘可能有益，我们建议进一步进行 RCT 并制定穴位药物注射疗法的标准方法。
