Bohn Olga L, Kalmar John R, Allen Carl M, Kirsch Claudia, Williams Dayna, Leon Marino E
Department of Pathology, MetroHealth Medical Center-Case Western Reserve University, Cleveland, OH 44109, USA.
Head Neck Pathol. 2011 Mar;5(1):71-5. doi: 10.1007/s12105-010-0212-4. Epub 2010 Oct 16.
Ossifying fibroma (OF) is a fibro-osseous tumor that usually occurs in young people and arises in the craniofacial bones. We report a case of a 15-year-old boy who developed progressive proptosis and hypertelorism and was found to have a mid-face and skull base tumor, initially diagnosed as psammomatoid meningioma. The tumor recurred and the resected specimen revealed a unique OF having trabecular and psammomatoid features. The clinical, radiographic, histopathologic findings and differential diagnoses of the case are presented.
骨化性纤维瘤（OF）是一种纤维骨性肿瘤，通常发生于年轻人，起源于颅面骨。我们报告一例15岁男孩，其出现进行性眼球突出和眼距增宽，被发现患有面中部和颅底肿瘤，最初诊断为砂粒体性脑膜瘤。肿瘤复发，切除标本显示为具有小梁状和砂粒体样特征的独特骨化性纤维瘤。本文介绍了该病例的临床、影像学、组织病理学表现及鉴别诊断。
