Zhang Zhi-Yuan, Min Mei-Ping, Liu Yang, Jiang Hong-Qun, Zhang Jian
Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Mol Clin Oncol. 2017 Feb;6(2):167-169. doi: 10.3892/mco.2016.1104. Epub 2016 Dec 7.
The psammomatoid ossifying fibroma (POF) is a rare and benign fibro-osseous lesion predominantly affecting the paranasal sinuses and orbits of children and young adults. The diagnosis and management of the lesion remains challenging. The present study reported a rare case of a large POF in a 39-year-old male patient. The patient had a 30 year history of a slowly growing tumor and this had resulted in right craniofacial deformity, as well as right lateral displacement of the eye ball. Due to the large tumor size, surgical removal of the lesion was the predominant treatment. At 5 months after complete surgical resection, the patient was free from any symptoms. The radiological and histological findings, as well as the surgical management, were presented and the relevant literature was reviewed.
砂粒体样骨化性纤维瘤(POF)是一种罕见的良性纤维骨性病变,主要影响儿童和年轻人的鼻窦和眼眶。该病变的诊断和治疗仍然具有挑战性。本研究报告了一例罕见的39岁男性患者的大型POF病例。患者有一个缓慢生长的肿瘤30年病史,这导致了右颅面畸形以及眼球向右外侧移位。由于肿瘤体积较大,手术切除病变是主要治疗方法。在完全手术切除后5个月,患者没有任何症状。本文展示了放射学和组织学结果以及手术治疗情况,并对相关文献进行了综述。