Tatibouet L, Morin P P, Griffe J
Sem Hop. 1978 Jan 9;54(2):101-6.
Primary hyperaldosteronism usually causes moderate hypertension. It is rare to note as in our two patients intermittent attacks of paroxysmal hypertension. The diagnosis of aldosteronism will be suspected on the finding of persistent hypokalemia with acidosis. It will be confirmed by laboratory examinations severe fall in plasma renin activity and rise in aldosterone in the adrenal veins. To determine the affected side, one may carry out adrenal phlebography which is a difficult technic, and/or a scan using iodine cholesterol which is benign and precise. Surgery with removal of the adenomatous hyperplasia in one case and of an adenoma in the other, gave one very good result.
原发性醛固酮增多症通常导致中度高血压。像我们的两位患者那样出现阵发性高血压的间歇性发作情况较为罕见。发现持续性低钾血症伴有酸中毒时,会怀疑有醛固酮增多症。通过实验室检查确诊,即血浆肾素活性严重降低以及肾上腺静脉中醛固酮升高。为确定患侧,可进行肾上腺静脉造影(这是一项难度较大的技术),和/或使用碘胆固醇进行扫描(这种方法无害且精确)。手术切除一例的腺瘤样增生和另一例的腺瘤,效果非常好。