Miyata Eye Hospital, Miyazaki, Japan.
J Refract Surg. 2011 May;27(5):339-44. doi: 10.3928/1081597X-20101005-02. Epub 2010 Oct 15.
To examine the efficacy and safety of topography-based limbal relaxing incision (LRI) surgery.
Forty-four eyes of 36 consecutive patients who underwent cataract surgery more than 1 month previously, had refractive against-the-rule astigmatism of ≥2.00 diopters (D), and were scheduled to undergo LRI surgery were enrolled in the study. Patients were randomized into two groups-a topography-based LRI group (19 eyes of 14 patients) and a conventional LRI group (25 eyes of 22 patients). The topography-based LRI procedure comprised 3 steps: placing a mark on the cornea and conjunctiva, identifying this mark in the topographic image, and performing LRI based on the location of the mark. In the conventional LRI group, the horizontal meridian was marked under a slit lamp and LRIs were made based on the position of the horizontal mark.
Corneal astigmatism in the topography-based LRI group before and 1 month after surgery was 2.03±0.92 D and 1.33±0.69 D, respectively (P=.014). Corneal astigmatism in the conventional LRI group before and 1 month after surgery was 2.36±0.77 D and 0.93±0.70 D, respectively (P<.0001). Fourier harmonic analysis of the topography data demonstrated that regular astigmatism was significantly decreased in the two groups. The mean regular astigmatism was not significantly different before and after LRI between groups, whereas the variances (mean of the deviation squared from its mean) of regular astigmatism were significantly different between groups 1 month after LRI.
Compared with conventional LRI surgery, a topography-based procedure may reduce the deviation of the effect of LRIs.
研究基于角膜地形的周边松解切口术(LRI)的疗效和安全性。
本研究共纳入 44 只眼(36 例连续患者),这些患者均于 1 个月前接受白内障手术,存在逆规性散光≥2.00 屈光度(D),并计划接受 LRI 手术。患者被随机分为两组:基于角膜地形的 LRI 组(14 例患者 19 只眼)和常规 LRI 组(22 例患者 25 只眼)。基于角膜地形的 LRI 手术包括 3 个步骤:在角膜和结膜上做标记、在地形图上识别该标记、根据标记位置行 LRI。在常规 LRI 组,在裂隙灯下标记水平子午线,并根据水平标记的位置进行 LRI。
基于角膜地形的 LRI 组术前和术后 1 个月的角膜散光分别为 2.03±0.92 D 和 1.33±0.69 D(P=.014)。常规 LRI 组术前和术后 1 个月的角膜散光分别为 2.36±0.77 D 和 0.93±0.70 D(P<.0001)。基于地形数据的傅里叶谐波分析表明,两组的规则散光均显著降低。两组术后的规则散光平均值与术前相比无显著差异,而术后 1 个月时规则散光的方差(规则散光平均值与其平均值的偏离平方的平均值)在两组间有显著差异。
与常规 LRI 手术相比,基于角膜地形的手术可能会降低 LRI 效果的偏差。