影响胎盘和胎儿体重的父母因素。
Parental factors affecting the weights of the placenta and the offspring.
机构信息
Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, The Netherlands.
出版信息
J Perinat Med. 2011 Jan;39(1):27-34. doi: 10.1515/jpm.2010.119. Epub 2010 Oct 18.
AIM
To determine parental, especially paternal factors associated with the weight of the placenta and offspring.
METHODS
This population-based birth-cohort study includes 2947 singleton children born from April 2006 to 2007 and living in Drenthe, The Netherlands. Placental weight and birth weight were measured and questionnaires were filled out for this cohort. Associations between parental factors, and the weight of the placenta and the offspring were evaluated using univariate and multivariate linear regression models.
RESULTS
Univariate regression revealed that the paternal birth weight and body mass index (BMI) of the father were predictors for placental and birth weight of the offspring. However, they were not independent predictors. Independent predictors for placental weight were the maternal factors of pre-pregnancy BMI, birth weight, and diabetes. The maternal factors of weight gain during pregnancy, birth weight, smoking during pregnancy, and diabetes were independent predictors for birth weight of the offspring.
CONCLUSION
Paternal as well as maternal factors influence the weight of the placenta and the offspring.
目的
确定与胎盘和后代体重相关的父母因素，特别是父亲的因素。
方法
本基于人群的出生队列研究包括 2006 年 4 月至 2007 年在荷兰德伦特省出生的 2947 名单胎儿童，并对其进行了研究。测量了胎盘重量和出生体重，并为该队列填写了调查问卷。使用单变量和多变量线性回归模型评估了父母因素与胎盘和后代体重之间的关联。
结果
单变量回归显示，父亲的出生体重和体重指数（BMI）是预测后代胎盘和出生体重的因素。但是，它们不是独立的预测因素。胎盘重量的独立预测因素是母亲的孕前 BMI、出生体重和糖尿病。母亲的孕期体重增加、出生体重、孕期吸烟和糖尿病是后代出生体重的独立预测因素。
结论
父亲和母亲的因素都会影响胎盘和后代的体重。
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