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儿童和青少年的偶发性双房室结生理现象:临床随访及意义

Incidental dual atrioventricular nodal physiology in children and adolescents: clinical follow-up and implications.

作者信息

McCanta Anthony C, Collins Kathryn K, Schaffer Michael S

机构信息

Division of Cardiology, Department of Pediatrics, The Children's Hospital, University of Colorado Denver School of Medicine, Denver, CO 80045-7106, USA.

出版信息

Pacing Clin Electrophysiol. 2010 Dec;33(12):1528-32. doi: 10.1111/j.1540-8159.2010.02880.x. Epub 2010 Oct 18.

Abstract

BACKGROUND

Dual atrioventricular (AV) nodal physiology is a substrate for the development of AV nodal reentrant tachycardia (AVNRT). However, the risk of developing AVNRT in patients with dual AV nodal physiology is not known. The purpose of this study is to identify the risk of developing AVNRT in children and adolescents with incidental findings of dual AV nodal physiology after accessory pathway ablation.

METHODS

This is a single center retrospective study of patients who underwent intracardiac electrophysiology study at The Children's Hospital, Denver, from March 1993 to August 2008, with findings of dual AV nodal physiology after successful ablation of an accessory pathway. Follow-up was obtained by chart review with the primary outcome of recurrent supraventricular tachycardia. Extended clinical follow-up was also achieved through phone contact with patients or parents of patients.

RESULTS

Mean age at initial electrophysiology study was 12.8 years (±3.7 years). Follow-up was obtained on all 66 patients for a mean duration of 3.1 years (±2.8 years). Mean age at follow-up was 15.8 years (±4.6 years). Recurrent supraventricular tachycardia occurred in nine of the 66 patients (13.6%). AVNRT was induced in two of the 66 patients (3.0%).

CONCLUSION

This study supports the hypothesis that incidental dual AV nodal physiology does not predict AVNRT in children and adolescents with after successful accessory pathway ablation.

摘要

背景

双房室结生理是房室结折返性心动过速(AVNRT)发生的一个基质。然而,双房室结生理患者发生AVNRT的风险尚不清楚。本研究的目的是确定在成功消融旁路后偶然发现双房室结生理的儿童和青少年中发生AVNRT的风险。

方法

这是一项单中心回顾性研究,研究对象为1993年3月至2008年8月在丹佛儿童医院接受心内电生理检查的患者,这些患者在成功消融一条旁路后发现有双房室结生理。通过查阅病历获得随访结果,主要结局为复发性室上性心动过速。还通过与患者或患者父母电话联系实现了延长的临床随访。

结果

初次电生理检查时的平均年龄为12.8岁(±3.7岁)。对所有66例患者进行了随访,平均随访时间为3.1年(±2.8年)。随访时的平均年龄为15.8岁(±4.6岁)。66例患者中有9例(13.6%)发生复发性室上性心动过速。66例患者中有2例(3.0%)诱发了AVNRT。

结论

本研究支持以下假设:在成功消融旁路后的儿童和青少年中,偶然发现的双房室结生理不能预测AVNRT。

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