Ferraz M B, Sesso R, Atra E
Escola Paulista de Medicina, Disciplina de Reumatologia, Rua Botucatu, São Paulo.
Rev Paul Med. 1990 Jul-Aug;108(4):153-6.
The authors discuss the usefulness of the HLA-B27 test in the diagnosis of ankylosing spondylitis (AS). Sensitivity, Specificity, Predictive Value of a Negative Test, Predictive Value of a Positive Test, and Likelihood Ratio are defined and illustrated through the example involving HLA-B27 and AS. The HLA-B27 cannot be used as a screening test for the diagnosis of AS when evaluating an asymptomatic population, however the test is most useful in assisting the diagnosis of AS when used by physicians who understand the principles of probability.
作者们讨论了HLA - B27检测在强直性脊柱炎（AS）诊断中的作用。通过涉及HLA - B27和AS的例子对灵敏度、特异性、阴性检测预测值、阳性检测预测值以及似然比进行了定义和说明。在评估无症状人群时，HLA - B27不能用作AS诊断的筛查检测，然而，对于理解概率原理的医生而言，该检测在辅助AS诊断方面最为有用。
