D'Orsi Carl J
Department of Radiology, Breast Imaging Center, Emory University Hospital, WCI Bldg, 1365-C Clifton Rd, Ste C1104, Atlanta, GA 30322, USA.
J Natl Cancer Inst Monogr. 2010;2010(41):214-7. doi: 10.1093/jncimonographs/lgq037.
Diagnosis of ductal carcinoma in situ (DCIS) has increased dramatically in parallel with the increased use of screening mammography. There are specific mammographic findings, most associated with shapes (amorphous, fine and coarse pleomorphic, and fine linear) and distributions (linear and segmental) of calcifications that permit a reasonable sensitivity for detection of DCIS without an unreasonable decrease in specificity, especially in view of the dramatic decrease in breast cancer mortality associated with early detection. While some DCIS may never progress to invasive disease, at this time, we cannot make that separation. This should be an active area for research.
导管原位癌（DCIS）的诊断率随着乳腺钼靶筛查的广泛应用而显著上升。乳腺钼靶有特定的表现，多数与钙化的形态（无定形、细和粗的多形性、细线性）及分布（线性和节段性）相关，这些表现能够在不显著降低特异性的情况下，对DCIS的检测具有合理的敏感性，特别是考虑到早期检测与乳腺癌死亡率的显著降低相关。虽然一些DCIS可能永远不会发展为浸润性疾病，但目前我们还无法区分。这应该是一个活跃的研究领域。
