Shanghai Jiao Tong University, People's Republic of China.
Appl Microbiol Biotechnol. 2011 Feb;89(3):523-34. doi: 10.1007/s00253-010-2938-z. Epub 2010 Oct 19.
Whether direct availability of organic compound solubilized in nonionic surfactant micelles (bioavailability) in a bioremediation or biotransformation process is uncertain to some extent, which is partially attributed to the difficulty by direct experimental determination. In another point of view, it should be ascribed to the fuzzy concept about the solubilization of organic compound in a nonionic surfactant micelle aqueous solution. In this mini-review, the solubilization of organic compound in surfactant micelles aqueous solution is fully discussed; especially saturated solubilization and unsaturated solubilization have been emphasized. Then the current methods for estimation of bioavailability of organic compounds solubilized in micelles are introduced, in which the possible drawbacks of each method are stressed. Finally, the conclusion that organic compound solubilized in micelles is unavailable directly by microbes has been drawn and the intensification of bioremediation or biotransformation by nonionic surfactant micelle aqueous solution is contributed to enhancement of the hydrophobic organic compounds dissolution.
在生物修复或生物转化过程中，有机化合物是否直接溶解在非离子表面活性剂胶束中（生物利用度）在某种程度上是不确定的，这在一定程度上归因于直接实验测定的困难。从另一个角度来看，这应该归因于非离子表面活性剂胶束水溶液中有机化合物溶解的模糊概念。在这篇综述中，充分讨论了有机化合物在表面活性剂胶束水溶液中的溶解，特别是强调了饱和溶解和不饱和溶解。然后介绍了估算胶束中溶解的有机化合物生物利用度的当前方法，强调了每种方法的可能缺点。最后得出结论，微生物不能直接利用胶束中溶解的有机化合物，并认为非离子表面活性剂胶束水溶液增强了疏水性有机化合物的溶解，从而强化了生物修复或生物转化。
